Thomas Brott
|
Research Investigator |
Location:
Mayo Clinic Jacksonville
Education:
Graduate School of Arts and Sciences, Harvard University, Special Student
1969 - 1970 University of Chicago, MD 1970 - 1974 University of Chicago Pritzker School of Medicine
Urban Studies Fellowship1971 - 1972
Beth Israel Hospital, Harvard Medical School
Internship, Medicine1974 - 1975 Harvard University
Fellowship, Clinical Fellow in Neurology1975 - 1978 Harvard Longwood Neurology Program, Beth Israel Hospital/Children's Hospital/Brigham and Women's Hospital
Residency, Neurology1975- 1978
Primary Academic Appointments:
Professor of Neurology - College of Medicine, Mayo Clinic
Consultant - Department of Neurology, Mayo Clinic
Director for Research - Mayo Clinic Research Committee
Associate Dean for Research, Mayo Foundation for Medical Education and Research
Awards and Recognition:
Cum laude in general studies - Harvard College, 1969
Urban Studies Fellowship - University of Chicago Pritzker School of Medicine, 1971-1972
Representative for Division of Biological Sciences to the President's Seminar - University of Chicago (One representative per Division), 1973-1974
Alpha Omega Alpha, 1974
Upjohn Achievement Award in Medicine - University of Chicago, 1974
Best Doctors - Best Doctors, Inc, 1992 - 2008
Stroke Council William Feinberg Award for Excellence in Clinical Stroke - American Heart Association, 1997
Research Merit Award - American Heart Association, Ohio-West Virginia Affiliate, 1997
Samuel Kaplan, M.D. Visionary Award for Excellence in Research - Cincinnati Division, American Heart Association, 1998
Robert E. and Clarice Smith Fellowship, 1999-2000
Recent Publications:
Meschia JF, Kissela BM, Brott TG, Brown RD Jr, Worrall BB, Beck J, Skarp AN. The Siblings With Ischemic Stroke Study (SWISS): a progress report. Clin Med Res 2006 Mar; 4(1):12-21.
Dominguez R, Vila JF, Augustovski F, Irazola V, Castillo PR, Escalante RR, Brott TG, Meschia JF. Spanish cross-cultural adaptation and validation of the National Institutes of Health Stroke Scale. Mayo Clin Proc 2006 Apr; 81(4):476-80.
Levy JH, Fingerhut A, Brott T, Langbakke IH, Erhardtsen E, Porte RJ. Recombinant factor VIIa in patients with coagulopathy secondary to anticoagulant therapy, cirrhosis, or severe traumatic injury: review of safety profile. Transfusion 2006 Jun; 46(6):919-33.
He Z, Meschia JF, Brott TG, Dickson DW, Mckinney M. Aging is neuroprotective during global ischemia but leads to increased caspase-3 and apoptotic activity in hippocampal neurons. Current Neurovascular Research 2006 Aug; 3(3):181-6.
Jauch EC, Lindsell CJ, Adeoye O, Khoury J, Barsan W, Broderick J, Pancioli A, Brott T. Lack of evidence for an association between hemodynamic variables and hematoma growth in spontaneous intracerebral hemorrhage. Stroke 2006 Aug; 37(8):2061-5.
Meschia JF, Case LD, Worrall BB, Brown RD, Brott TG, Frankel M, Silliman S, Rich SS. Family history of stroke and severity of neurologic deficit after stroke. Neurology 2006 Oct 24; 67(8):1396-402.
Barrett KM, Brott TG. Carotid artery stenting versus carotid endarterectomy: Current status. Neurol Clin 2006 Nov; 24(4):681-95.
Meschia JF, Barrett KM, Chukwudelunzu F, Brown WM, Case LD, Kissela BM, Brown RD Jr, Brott TG, Olson TS, Rich SS, Silliman S, Worrall BB, Siblings with Ischemic Stroke Study (SWISS) Investigators. Interobserver agreement in the trial of org 10172 in acute stroke treatment classification of stroke based on retrospective medical record review. J Stroke Cerebrovasc Dis 2006 Nov-Dec; 15(6):266-72.
Barrett KM, Brott TG, Brown RD Jr, Frankel MR, Worrall BB, Silliman SL, Case LD, Rich SS, Meschia JF, Ischemic Stroke Genetics Study Group. Sex differences in stroke severity, symptoms, and deficits after first-ever ischemic stroke. J Stroke Cerebrovasc Dis 2007 Jan-Feb; 16(1):34-9.
Brott TG. Novel approaches to stroke prevention in atrial fibrillation: introduction. Stroke 2007 Feb; 38(2 Suppl):614.
Wiklund PG, Brown WM, Brott TG, Stegmayr B, Brown RD, Nilsson-Ardnor S, Hardy JA, Kissela BM, Singleton A, Holmberg D, Rich SS, Meschia JF. Lack of aggregation of ischemic stroke subtypes within affected sibling pairs. Neurology 2007 Feb 6; 68(6):427-31.
Worrall BB, Brott TG, Brown RD Jr, Brown WM, Rich SS, Arepalli S, Wavrant-De Vrieze F, Duckworth J, Singleton AB, Hardy J, Meschia JF, SWISS, ISGS and MSGD I. IL1RN VNTR polymorphism in ischemic stroke: analysis in 3 populations. Stroke 2007 Apr; 38(4):1189-96.
Matarin M, Brown WM, Scholz S, Simon-Sanchez J, Fung HC, Hernandez D, Gibbs JR, De Vrieze FW, Crews C, Britton A, Langefeld CD, Brott TG, Brown RD Jr, Worrall BB, Frankel M, Silliman S, Case LD, Singleton A, Hardy JA, Rich SS, Meschia JF. A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. Lancet Neurol 2007 May; 6(5):414-20.
Barrett KM, Freeman WD, Weindling SM, Brott TG, Broderick DF, Heckman MG, Crook JE, Divertie GD, Meschia JF. Brain injury after cardiopulmonary arrest and its assessment with diffusion-weighted magnetic resonance imaging. Mayo Clin Proc 2007 Jul; 82(7):828-35.
Meschia JF, Brott TG, Hobson RW 2nd. Diagnosis and invasive management of carotid atherosclerotic stenosis. Mayo Clin Proc 2007 Jul; 82(7):851-8.
Thompson KM, Gerlach SY, Jorn HK, Larson JM, Brott TG, Files JA. Advances in the care of patients with intracerebral hemorrhage. Mayo Clin Proc 2007 Aug; 82(8):987-90.
Leslie-Mazwi TM, Brott TG, Brown RD Jr, Worrall BB, Silliman SL, Case LD, Frankel MR, Rich SS, Meschia JF. Sex differences in stroke evaluations in the Ischemic Stroke Genetics Study. J Stroke Cerebrovasc Dis 2007 Sep-Oct; 16(5):187-93.
Matarin M, Brown WM, Hardy JA, Rich SS, Singleton AB, Brown RD Jr, Brott TG, Worrall BB, Meschia JF, SWISS Study Group, ISGS Study Group, MSGD Study Group. Association of integrin alpha2 gene variants with ischemic stroke. J Cereb Blood Flow Metab 2008 Jan; 28(1):81-9 Epub 2007 May 30.
Hughes SE, Tom M, Longbottom ME, Sheffet AJ, Brott TG, Hobson RW II. CREST Update: Meeting the challenges of a randomized clinical trial. Endovas Today 2007; 6(9):1-3.
Barrett KM, Brott TG. Carotid endarterectomy versus angioplasty/stenting for carotid stenosis. Curr Atheroscler Rep 2007 Oct; 9(4):333-40.
Pancioli A, Broderick J, Brott T, Tomsick T, Khoury J, Bean J, del Zoppo G, Janis S, Kleindorfer D, Woo D, Khatri P, Castaldo J, Frey J, Gebel J, Kasner S, Kidwell C, Kwiatkowski T, Libman R, Mackenzie R, Scott P, Starkman S, Thurman J. The Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke. Stroke 2008(Version 1). [Epub ahead of print]
Contact Information:
Mayo Clinic Jacksonville
4500 San Pablo Road
Jacksonville, FL 32224
904-953-7104
Fax: 352-273-6109
E-mail: Brott.Thomas@mayo.edu